They do not contain gluten, lactose, sucrose, tartrazine or any other azo dyes. Each tablet contains 250 mg acetazolamide.ĭiamox tablets also contain the inactive ingredients sodium starch glycollate, povidone, calcium hydrogen phosphate dihydrate, maize starch, and magnesium stearate. The active ingredient in Diamox is acetazolamide. Alteration in ammonia metabolism occurs due to increased reabsorption of ammonia by the renal tubules as a result of urinary alkalinisation. Alkalinization of the urine and promotion of diuresis are thus effected. The result is renal loss of HCO3 ions, that carry out sodium, water and potassium. The diuretic effect of Diamox is due to its action in the kidney on the reversible reaction involving hydration of carbon dioxide and dehydration of carbonic acid. Inhibition of carbonic anhydrase in this area appears to retard abnormal, paroxysmal, excessive discharge from central nervous system neurons. Evidence seems to indicate that Diamox has utility as an adjuvant in the treatment of certain dysfunctions of the central nervous system (e.g. In the eye this inhibitory action of acetazolamide decreases the secretion of aqueous humour and results in a drop in intraocular pressure, a reaction considered desirable in cases of glaucoma and even in certain nonglaucomatous conditions. Diamox is an enzyme inhibitor that acts specifically on carbonic anhydrase, the enzyme that catalyses the reversible reaction involving the hydration of carbon dioxide and the dehydration of carbonic acid. This action helps people with congestive heart failure or fluid retention caused by other medicines.ĭiamox is a nonbacteriostatic sulfonamide possessing a chemical structure and pharmacological activity distinctly different from the bacteriostatic sulfonamides. This gets rid of excess fluid in the body by increasing urine production. ![]() ![]() This helps prevent fits in people with epilepsy. ![]() Blocking this enzyme also seems to slow down abnormal or excessive discharge from your nerves. In people with glaucoma, blocking this enzyme causes the pressure in the eye caused by fluid build-up to fall. Diamox works by blocking an enzyme, which is responsible for fluid formation.
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